One of the most valuable aspects of propolis for both humans and bees is its natural antiseptic qualities.

Propolis is one of the natural remedies that has been popular for a long time. The pharmacologically active molecules in propolis are flavonoids and phenolic acids and their esters. These components have many effects on bacteria, fungi and viruses. In addition, propolis and its components have anti-inflammatory and immunomodulatory activities. Propolis has also been shown to lower blood pressure and cholesterol levels. However, clinical studies are needed to prove these claims.

By spreading propolis or its extract on wounds, you can protect open wounds and cuts, which are much more serious, from infection.

Secondly, its antioxidants can accelerate wound healing by reducing inflammation, ensuring healthy blood flow in these areas. Propolis has traditionally been used to treat wounds, insect bites, burns, skin disorders, and boils. Scientific documentation of its wound healing properties confirms its effectiveness as a wound repair promoter and antimicrobial agent. It promotes the activation of immobilized plasminogen in the wound matrix, resulting in the dynamic expression of the proteolytic enzyme. Plasmin causes blood clot retraction and fibrin degradation. It is an enzyme that breaks down fibrin clots with attached dead tissue in the wound bed.

Bad odor is a general feature of serious wounds caused by anaerobic bacterial species belonging to Bacteroides spp. and Peptostreptococcus spp. . Malicious compounds such as ammonia, amines and sulfur are produced by bacteria during the metabolism of amino acids from the deposited serum and tissue proteins. These compounds replace lactic acids by distributing a significant amount of glucose, a substrate metabolized by bacteria, with preference for amino acids. Therapeutic effects observed after propolis application include rapid healing, wound cleansing, clearance of pus, tissue degeneration, minimized inflammation and effective dressing due to low tissue adhesion.

In a similar situation, it can also be used as an anti-inflammatory cream for insect bites and other skin conditions that are not technically classified as wounds. The phytochemical compounds that contribute to the anti-inflammatory effect of propolis have been used for thousands of years to treat insect bites, rashes, and all kinds of skin irritations with either secretions made with propolis or by applying the substance directly to the skin. These have even proven effective for treating acne, psoriasis, eczema, and other infections in our body's largest organ.